Understanding Allergy Therapy: Benefits, Risks, and How It Works

Understanding Allergy Therapy: Benefits, Risks, and How It Works
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Published:
January 27, 2025
Updated:
August 18, 2025

Allergies are more than just a seasonal nuisance—they can disrupt sleep, affect productivity, and reduce quality of life. Millions of people in the United States and around the world live with allergic conditions, from hay fever and pet allergies to dust mite and mold sensitivities. While medications can help manage symptoms, they do not address the underlying cause. That’s where allergy therapy, also known as allergen immunotherapy, comes in.

In this comprehensive guide, we’ll explore what allergy therapy is, how it works, the benefits and risks, and what you can realistically expect if you choose this treatment path.

What Is Allergy Therapy?

Allergy therapy is a long-term medical treatment designed to “retrain” the immune system so it stops overreacting to harmless substances like pollen, dust, or pet dander. Instead of masking symptoms, it addresses the root cause of allergies.

It works by introducing tiny, controlled amounts of the allergen into the body, either by injection or under the tongue. Over time, the immune system becomes less sensitive, reducing or even eliminating allergic reactions.

The two most widely used forms are:

  • Allergy Shots (Subcutaneous Immunotherapy – SCIT)
    Involves small injections under the skin, typically given in a doctor’s office. Most effective for pollen, mold, dust mites, pet dander, and insect stings.
  • Allergy Drops or Tablets (Sublingual Immunotherapy – SLIT)
    Medication placed under the tongue at home. Convenient and increasingly popular for pollen, dust, and some environmental allergens.

Who Can Benefit From Allergy Therapy?

Allergy therapy is often recommended for people who:

  • Experience moderate to severe allergy symptoms year-round or during peak seasons.
  • Do not respond well to antihistamines, nasal sprays, or other medications.
  • Want a long-term solution instead of temporary symptom relief.
  • Have allergic asthma triggered by environmental allergens.
  • Prefer to reduce their dependence on daily medications.

Benefits of Allergy Therapy

Unlike standard medications that only “quiet” symptoms, allergy therapy creates lasting immune changes. Benefits include:

  • Long-lasting relief – Many patients continue to feel better years after therapy ends.
  • Fewer medications – A reduced need for antihistamines and steroid sprays.
  • Better quality of life – Less sneezing, congestion, itchy eyes, and fatigue.
  • Reduced risk of new allergies – Studies suggest it may prevent additional sensitivities from developing.
  • Asthma prevention – Early treatment can lower the chance of developing allergic asthma.
  • Cost savings over time – Though upfront costs exist, patients often spend less on long-term medications and doctor visits.

Risks and Side Effects

Allergy therapy is generally safe when prescribed and monitored by a board-certified allergist. Still, it carries some risks:

  • Mild reactions – Redness or swelling at the injection site (SCIT) or temporary mouth irritation (SLIT).
  • Worsening symptoms early on – Some patients notice flare-ups before improvement begins.
  • Severe allergic reactions (rare) – Anaphylaxis is possible, which is why therapy must always start under medical supervision.
  • Commitment needed – Results take time; missing doses reduces effectiveness.

How to Prepare for Allergy Therapy

Before starting, your allergist will:

  1. Take a detailed history – Symptoms, lifestyle, and triggers.
  2. Perform allergy testing – Usually skin tests or blood tests to confirm exact allergens.
  3. Explain the process – Including how long therapy will take and what to expect.
  4. Set realistic expectations – This is a marathon, not a sprint.
  5. Review medications – Some medicines may need to be adjusted before therapy.

How Allergy Therapy Works

Treatment typically has two phases:

  1. Build-Up Phase
    • Lasts about 3–6 months.
    • Gradually increasing doses of the allergen.
    • Requires frequent visits (for shots) or daily use (for drops/tablets).
  2. Maintenance Phase
    • Lasts 3–5 years for most patients.
    • The “steady state” dose keeps the immune system tolerant.
    • Visits are less frequent, often once every 4–6 weeks for shots.

When do results show?
Many patients notice improvement within 6–12 months. The full benefit typically comes after 2–3 years.

Life After Allergy Therapy

The results can be life-changing:

  • Fewer flare-ups during allergy season.
  • Reduced dependence on daily medication.
  • Improved sleep and energy levels.
  • Lasting tolerance that can continue even after therapy stops.

It’s important to continue follow-up visits, track symptoms, and maintain good allergen-avoidance habits for the best outcome.

Types of Allergy Immunotherapy at a Glance

  • Subcutaneous Immunotherapy (Allergy Shots)
    • In-office only.
    • Best for multiple allergens.
  • Sublingual Immunotherapy (Drops or Tablets)
    • At-home option.
    • Safe and convenient.
  • Emerging Therapies
    • Biologic drugs targeting immune pathways.
    • Gene therapy is being researched but not yet widely available.

Post-Treatment Care

Even after finishing therapy, you’ll want to:

  • Keep regular check-ups with your allergist.
  • Track symptoms to monitor changes.
  • Maintain a clean home environment (dust-mite covers, HEPA filters, etc.).
  • Avoid unnecessary allergen exposure when possible.

Conclusion

Allergy therapy is more than symptom management—it’s a path to long-term relief by addressing the immune system directly. With the right treatment plan, many patients experience fewer allergies, less medication use, and better overall health.

If allergies are affecting your quality of life, consulting a board-certified allergist is the first step. At HeyAllergy, our specialists offer personalized telemedicine care and custom treatment plans, including sublingual immunotherapy.

Book your appointment today and start your journey toward lasting allergy relief.

Frequently Asked Questions About Allergy Therapy

What is allergy therapy?
It’s a long-term treatment that retrains the immune system to tolerate allergens, reducing symptoms over time.

How long does it take to work?
Many people feel better within the first year, but full results usually take 3–5 years.

Is it safe?
Yes, when administered by a trained allergist. Severe reactions are rare but possible.

Will I still need medications?
Most patients reduce or eliminate their need for daily allergy medications after successful therapy.

Can it prevent asthma?
Early allergy therapy may reduce the risk of developing allergic asthma later in life.

Ready to treat your allergies with expert care?

Book an online appointment now with our board-certified allergists and start feeling better!