What is the Difference Between Allergy Shots and Allergy Drops?

Navigating the world of allergy treatments can be overwhelming, especially when deciding between options like allergy shots and allergy drops. Both are forms of immunotherapy, offering long-term solutions to allergic reactions, but they differ in administration, convenience, patient experience, and suitability for different lifestyles. This blog post delves into the nuances of both treatments to help you understand which might be the best fit for your allergy management.

Allergy Shots: An In-Depth Look

Allergy shots, or subcutaneous immunotherapy, have been a cornerstone in allergy treatment for many years. Their key characteristics include:

  1. Injection Method: This traditional method involves injecting small quantities of allergens under the skin. This procedure is typically done in the upper arm and requires precision and medical supervision.
  2. Clinic Visits: Initially, patients receive these injections frequently, usually once or twice a week. These visits are essential as they allow healthcare providers to monitor reactions and adjust dosages.
  3. Gradual Increase in Dosage: Over time, the allergen concentration in each shot is increased. This gradual increase is crucial for building tolerance safely and effectively.
  4. Long-term Commitment: Completing the full course of allergy shots can take several years. Patients often notice a reduction in symptoms over time, with many achieving lasting relief even after the treatment has concluded.
  5. Effectiveness for Various Allergens: Allergy shots have been proven effective for a wide range of allergens, including environmental allergens like pollen, dust, and pet dander, as well as insect stings.

Allergy Drops: A Closer Look

Allergy drops, known scientifically as sublingual immunotherapy, offer a more recent approach to allergy treatment. Their features include:

  1. Sublingual Administration: The drops are placed under the tongue and absorbed directly into the bloodstream. This method leverages the rich vascular supply in the sublingual area for effective allergen delivery.
  2. Home Administration: A significant advantage of allergy drops is the ability to self-administer them at home. This convenience is a game-changer for many patients, especially those with busy schedules or limited access to healthcare facilities.
  3. Consistent Exposure to Allergens: The daily administration of allergy drops provides a steady, consistent exposure to allergens. This consistency is key in building up tolerance over time.
  4. Safety and Convenience: Generally, allergy drops are associated with fewer risks of severe allergic reactions compared to shots. This safety profile makes them a viable option for a broader range of patients, including children.
  5. Suitability for Various Lifestyles: Allergy drops are especially suitable for those who are needle-phobic, have hectic schedules, or prefer the convenience of home treatment.

Comparing Allergy Shots and Drops

  1. Administration Method: The fundamental difference lies in their administration—shots are invasive and given via injection, while drops are non-invasive and administered orally.
  2. Location of Treatment: Allergy shots necessitate regular clinic visits for administration and observation, whereas allergy drops offer the flexibility and comfort of being taken at home.
  3. Frequency of Treatment: Allergy shots are typically less frequent but require a long-term commitment to regular appointments. In contrast, allergy drops are taken daily, providing more consistent allergen exposure.
  4. Safety Profile: The risk of severe allergic reactions, while small, is present with allergy shots, thus requiring medical supervision. Allergy drops have a lower risk profile, making them suitable for unsupervised, at-home use.
  5. Individual Preferences and Lifestyles: The choice between shots and drops often depends on personal preferences, lifestyle considerations, and specific medical advice. Some may prefer the routine and medical supervision of shots, while others may value the convenience and autonomy of drops.


Understanding the differences between allergy shots and drops is crucial in making an informed decision about allergy treatment. Both methods offer effective ways to manage and alleviate allergy symptoms but cater to different needs and lifestyles. While shots have a long-standing record of efficacy, drops provide a modern, convenient alternative.Choosing between allergy shots and drops can be a significant decision in your allergy management journey. To make an informed choice, consult with our allergy specialists who can provide personalized advice based on your specific allergy profile, health status, and lifestyle considerations.

Frequently Asked Questions About Allergy Shots and Allergy Drops

Are allergy shots more effective than allergy drops?
Both allergy shots and drops are effective forms of immunotherapy. The effectiveness can vary based on individual response, the type of allergen, and adherence to the treatment regimen. Some people may respond better to shots, while others find drops more effective.

Can children use allergy drops or shots?
Yes, both allergy shots and drops are used in pediatric allergy treatment. However, due to their non-invasive nature and ease of use, allergy drops are often preferred for children.

How quickly can I expect to see results from allergy shots or drops?
Improvement in allergy symptoms can vary. Some people may notice changes within a few months, while for others, it may take a year or more. Consistency in treatment is key to seeing results.

Are there any side effects of allergy drops or shots?
Side effects for both treatments are generally mild. Allergy shots may cause redness or swelling at the injection site, while allergy drops may lead to itching or irritation in the mouth. Severe reactions are rare.

Is one treatment more cost-effective than the other?
The cost-effectiveness can vary depending on several factors, including insurance coverage and the frequency of clinic visits for allergy shots. Allergy drops, often administered at home, can reduce the number of healthcare visits, which may be a cost-saving factor for some.

Can I switch from allergy shots to drops or vice versa?
Switching between the two forms of treatment is possible, but it should be done under the guidance of an allergist. They can evaluate your response to treatment and decide the best course of action.

Do I need to take allergy drops or shots indefinitely?
The duration of treatment varies, but both allergy shots and drops are typically long-term treatments, often lasting several years. Your allergist can provide more specific guidance based on your progress and response.